Principal Investigator

Praveen Sethupathy, Ph.D. Professor of Physiological Genomics praveens@cornell.edu

Senior Research Associate
	Mike Shanahan, Ph.D. mts253@cornell.edu Senior Scientist and Lab Manager Mike has over 20 years of experience in the field of gastrointestinal physiology.  His main areas of research focus in the Sethupathy lab include genetic and environmental control of Paneth cells, as well as the role of microRNAs in regulating Paneth cell function.
	Bo Shui, Ph.D. bs222@cornell.edu Senior Scientist Bo has decades of experience as a senior scientist in molecular biology.  Currently he is providing expert capabilities in nuclei isolation and library preparation for single-cell ATAC and RNA sequencing.  Two major areas of focus include fibrolamellar carcinoma and oral squamous cell carcinoma (in collaboration with Santiago Peralta and Bill Katt).
Technician
	Alex Drake, B.S. add73@cornell.edu Technician Alex works closely with SRA Mike Shanahan to provide varied important technical support for the lab, ranging from mouse colony management to lab safety to the optimization of new bench techniques.  Alex also provides valuable training for junior scientists in the lab, including summer research students.
Postdoctoral Fellows
Alexandria (Alexx) Shumway, Ph.D. as3999@cornell.edu Postdoctoral Fellow Alexx completed her PhD in the lab on microRNAs and human IBD and now as a post-doc she will continue to study microRNAs but in the context of canine IBD, leveraging state-of-the-art high-resolution genome-scale technologies including spatial platforms.
Graduate Students
	Donald Long, B.S. dl964@cornell.edu Ph.D. Student (GGD) Don studies the tumor metabolism in the context of fibrolamellar carcinoma (FLC).  Specifically, he is interested in the role of an orphan transporter in promoting FLC tumor growth, as well as in specific microRNAs and their contribution to the regulation of glycolysis and FLC cell survival.
	Sunita Nepal sn635@cornell.edu Ph.D. Student (BBS) Sunita is co-mentored by Anushka Dongre (BMS), and her research focuses on the role of microRNAs in EMT-driven immunosuppression in breast cancer.  Her work involves genome-scale approaches to studying gene regulation, immunology, cell biology, as well as animal models of cancer.
	Andreas Stephanou as3562@cornell.edu Ph.D. Student (GGD) Andreas is co-mentored by Iwijn De Vlaminck (BME), and his research focuses on genome technology development, particularly in spatial transcriptomics, and its application to the study of health and disease.  One major area of focus is spatially resolving the tumor microenvironment in fibrolamellar carcinoma.
	Jenna Todero jet244@cornell.edu Ph.D. Student (BMCB) Jenna’s core interests are in physiology and metabolic disease.  Her thesis work is focused on the identification of the regulatory mechanisms that underpin the association between arsenic exposure and diabetes phenotypes.
Undergraduate Students
	Anwesa Brahmachary adb297@cornell.edu Undergraduate Student Anwesa is exploring the effects of diet on intestinal Paneth cell number, location, and function.
	Bhumika Iroji bji8@cornell.edu Undergraduate Student Bhumika is part of a team studying the genetic, molecular, and environmental control of Paneth cell biology.
	Renee Lee ryl27@cornell.edu Undergraduate Student Renee is studying how Paneth cells across different regions of the intestine respond to helminth infection.
	Shreekanya Mitra sm2822@cornell.edu Undergraduate Student Shree is investigating the mechanisms by which arsenic affects Paneth cell function in the gut.