Article: Serey X, Mandal S, Chen YF and Erickson D (2012). “DNA Transport and Delivery in Thermal Gradients near Optofluidic Resonators.” Physical Review Letters 108(4).
Abstract: Heat generation and its impact on DNA transport in the vicinity of an optofluidic silicon photonic crystal resonator are studied theoretically and experimentally. The temperature rise is measured to be as high as 57 K for 10 mW of input power. The resulting optical trapping and biomolecular sensing properties of these devices are shown to be strongly affected by the combination of buoyancy driven flow and thermophoresis. Specifically, the region around the electromagnetic hot spot is depleted in biomolecules because of a high free energy barrier.