°Identification of viral suppressors of RNA silencing of grapevine fanleaf virus

Here, we identify viral suppressors of RNA silencing (VSRs) encoded by grapevine fanleaf virus (GFLV). Using transgenic Nicotiana benthamiana plants, GFLV RNA1-encoded protein 1A and protein 1B^Hel reverse systemic RNA silencing either individually or as a fused form, 1AB^Hel. These VSRs also differenitally altered the expression of plant host genes involved in RNA silencing. This is the first report of VSRs encoded by RNA1 of a nepovirus and of two VSRs acting individually or in a fused form.

Choi  et al. (2023) MPMI