Here, Brandon summarizes changes in the proteome and transcriptome of Nicotiana benthamiana plants infected by grapevine fanleaf virus. Utilizing comparative, time-course liquid chromatography tandem mass spectrometry and sequence analysis, we show protein and gene ontologies related to immune response and gene regulation to be overrepresented at peak symptom observations. The systems biology approach taken in this work highlights the power of a single amino acid of plant viral RNA-dependent RNA polymerase to mediate changes in the host proteome and transcriptome.
°Profiling changes in the plant proteome and transcriptome during grapevine fanleaf virus infection
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