Cytochrome P450 monooxygenases (CYPs) carry out the detoxification of insecticides, and overexpression of one or more CYPs is a common mechanism of insecticide resistance in mosquitoes. Smith et al. investigated the molecular basis for CYP-mediated resistance in A. aegypti and found that overexpression of the CYPs responsible for resistance was due to a trans-regulatory factor. Read more
Understanding the causes of insecticide resistance in Aedes aegypti
March 13, 2019 By