Publications

At Cornell:

Pre-Print

In Press

Sridalla K*^&, Woodhouse M^&, Hu J, Scheer J*, Ferlez B, Crickard JB. The translocation activity of Rad54 reduces crossover outcomes during homologous recombination. Nucleic Acids Research (2024) PMID:38828785

Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Crickard JB, Alani E. The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease. Genetics (2024) PMID:38657110

Hu J and Crickard JB. All who wander are not lost: the search for homology during homologous recombination ( Biochemical Society Transactions)(2024) PMID: 38323621

Hu J, Ferlez B, Dau J, Crickard JB. Rad53 regulates Rdh54 lifetime of homologous recombination intermediates (2023) Nucleic Acids Research 2023 Oct. 18th. PMID: 37850655

Keymakh M, Dau J, Ferlez B, Hu J, Lisby M, Crickard JB. Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes (2022) PLOS Genetics PMID: 36099310

Crickard JB. Discrete roles for Rad54 and Rdh54 during homologous recombination. (2021) Current Opinion in Genetics and Development. PMID: 34293661

Before Cornell:

Crickard JB, Kwon Y, Sung P, Greene EC Rad54 and Rdh54 occupy spatially and functionally distinct sites within the Rad51-ssDNA presynaptic complex. (2020) EMBO J PMID: 32790929

Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC. Rad54 drives ATP-hydrolysis dependent DNA sequence alignment during homologous recombination (2020) Cell. PMID: 32502392

Zhenxin Yan, Xue C, Kuman S, Crickard JB, Yu Y, Wang W, Pham N, Li Y, Niu H, Sung P, Greene EC, Ira G. Rad52 attenuates resection of DNA double strand break ends in yeast. (2019) Molecular Cell. PMID: 31542296

Steinfeld JB, Belan O, Kwon, Y, Terakawa T, Al-Zain A, Smith MJ, Crickard JB, Qi Z, Zhao W, Rothstein R, Symington LS, Sung P, Boulton SJ, Greene EC. Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination. (2019) Genes Dev. PMID: 31371435

Crickard JB, Xue C, Wang W, Kwon Y, Sung P, Greene EC. The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments. (2019) Nucleic Acids Res. PMID: 30916344

Xue C, Wang W, Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC. (2019) Proceedings in the National Academy of Science. Regulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection. PMID: 30850524

Crickard JB and Reese JC. Biochemical Methods to characterize RNA polymerase II elongation complexes. (2019) Methods . PMID: 30684536

Lee J, Crickard JB, Reese JC, Lee TH. Single-molecule FRET method to investigate the dynamics of transcription elongation through the nucleosome by RNA polymerase II. (2019) Methods. PMID: 30660864

Crickard JB, Kwon Y, Sung P, Greene EC. Dynamic interactions of the Homologous Pairing 2 (Hop2)- Meiotic Nuclear Divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast. (2019) The Journal of Biological Chemistry. PMID: 30420424

Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC. Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase. (2018) Proceedings in the National Academy of Science PMID:30301803

Crickard JB, Kaniecki K, Kwon Y, Sung P, Lisby M, Greene EC Regulation of Hed1 and Rad54 binding during maturation of meiosis specific presynaptic complex. (2018) EMBO J. PMID: 29444896

Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC. Spontaneous self-segregation of Rad51 and Dmc1 within mixed recombinase filaments. (2018) The Journal of Biological Chemistry PMID: 29382724

De Tullio L, Kaniecki K, Kwon Y, Crickard JB, Sung P, Greene EC. Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation. (2017) Cell Reports. PMID: 29045827

 Crickard JB, Lee JY, Lee TH and Reese JC. The elongation factor Spt4/5 regulates RNA Polymerase II transcription through the nucleosome. (2017) Nucleic Acids Research. PMID: 28379497

 Crickard JB, Fu J, Reese JC. Biochemical analysis of yeast suppressor of Ty 4/5(Spt4/5) reveals the importance of nucleic acid interactions in the prevention of RNA Polymerase II arrest. (2016) The Journal of Biological Chemistry. PMID: 26945063

Highlighted in JBC’s best of 2016

Zheng S¹, Crickard JB¹, Srikanth A, Reese JC. A highly conserved region within H2B is important for FACT to act on nucleosomes. (2014) Molecular and Cellular Biology. PMID: 24248595

¹equal contribution

A perspective was also written about this publicationOsley MA. FACT and the H2B N Tail. (2014) Molecular and Cellular Biology. 34,300-302

Invited reviews:

Crickard JB, and Greene EC. Helicase Mechanisms During Homologous Recombination in Saccharomyces cerevisiae. (2019) Annual Review of Biophysics. PMID: 30857400

Crickard JB, Greene EC. Biochemical attributes of mitotic and meiotic presynaptic filaments. (2018) DNA Repair. PMID:30195641

Crickard JB, and Greene EC. The biochemistry of early meiotic recombination intermediates. (2018) Cell Cycle. PMID: 30482074