At Cornell:
Pre-Print
Pannafino G, Chen JJ, Mithani V, Payero L, Gioia M, Crickard JB, Alani E. The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease. BioRxiv (2023)
Sridalla K*&, Woodhouse M&, Hu J, Scheer J*, Ferlez B, Crickard JB. The DNA strand opening activity of Rad54 reduces crossover outcomes during homologous recombination. BioRxiv (2024)
In Press
Hu J and Crickard JB. All who wander are not lost: the search for homology during homologous recombination (Just Accepted, Biochemical Society Transactions)(2024)
Hu J, Ferlez B, Dau J, Crickard JB. Rad53 regulates Rdh54 lifetime of homologous recombination intermediates (2023) Nucleic Acids Research 2023 Oct. 18th. PMID: 37850655
Keymakh M, Dau J, Ferlez B, Hu J, Lisby M, Crickard JB. Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes (2022) PLOS Genetics PMID: 36099310
Crickard JB. Discrete roles for Rad54 and Rdh54 during homologous recombination. (2021) Current Opinion in Genetics and Development. PMID: 34293661
Before Cornell:
Crickard JB, Kwon Y, Sung P, Greene EC Rad54 and Rdh54 occupy spatially and functionally distinct sites within the Rad51-ssDNA presynaptic complex. (2020) EMBO J PMID: 32790929
Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC. Rad54 drives ATP-hydrolysis dependent DNA sequence alignment during homologous recombination (2020) Cell. PMID: 32502392
Zhenxin Yan, Xue C, Kuman S, Crickard JB, Yu Y, Wang W, Pham N, Li Y, Niu H, Sung P, Greene EC, Ira G. Rad52 attenuates resection of DNA double strand break ends in yeast. (2019) Molecular Cell. PMID: 31542296
Steinfeld JB, Belan O, Kwon, Y, Terakawa T, Al-Zain A, Smith MJ, Crickard JB, Qi Z, Zhao W, Rothstein R, Symington LS, Sung P, Boulton SJ, Greene EC. Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination. (2019) Genes Dev. PMID: 31371435
Crickard JB, Xue C, Wang W, Kwon Y, Sung P, Greene EC. The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments. (2019) Nucleic Acids Res. PMID: 30916344
Xue C, Wang W, Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC. (2019) Proceedings in the National Academy of Science. Regulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection. PMID: 30850524
Crickard JB and Reese JC. Biochemical Methods to characterize RNA polymerase II elongation complexes. (2019) Methods . PMID: 30684536
Lee J, Crickard JB, Reese JC, Lee TH. Single-molecule FRET method to investigate the dynamics of transcription elongation through the nucleosome by RNA polymerase II. (2019) Methods. PMID: 30660864
Crickard JB, Kwon Y, Sung P, Greene EC. Dynamic interactions of the Homologous Pairing 2 (Hop2)- Meiotic Nuclear Divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast. (2019) The Journal of Biological Chemistry. PMID: 30420424
Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC. Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase. (2018) Proceedings in the National Academy of Science PMID:30301803
Crickard JB, Kaniecki K, Kwon Y, Sung P, Lisby M, Greene EC Regulation of Hed1 and Rad54 binding during maturation of meiosis specific presynaptic complex. (2018) EMBO J. PMID: 29444896
Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC. Spontaneous self-segregation of Rad51 and Dmc1 within mixed recombinase filaments. (2018) The Journal of Biological Chemistry PMID: 29382724
De Tullio L, Kaniecki K, Kwon Y, Crickard JB, Sung P, Greene EC. Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation. (2017) Cell Reports. PMID: 29045827
Crickard JB, Lee JY, Lee TH and Reese JC. The elongation factor Spt4/5 regulates RNA Polymerase II transcription through the nucleosome. (2017) Nucleic Acids Research. PMID: 28379497
Crickard JB, Fu J, Reese JC. Biochemical analysis of yeast suppressor of Ty 4/5(Spt4/5) reveals the importance of nucleic acid interactions in the prevention of RNA Polymerase II arrest. (2016) The Journal of Biological Chemistry. PMID: 26945063
Highlighted in JBC’s best of 2016
Zheng S1, Crickard JB1, Srikanth A, Reese JC. A highly conserved region within H2B is important for FACT to act on nucleosomes. (2014) Molecular and Cellular Biology. PMID: 24248595
1equal contribution
A perspective was also written about this publicationOsley MA. FACT and the H2B N Tail. (2014) Molecular and Cellular Biology. 34,300-302
Invited reviews:
Crickard JB, and Greene EC. Helicase Mechanisms During Homologous Recombination in Saccharomyces cerevisiae. (2019) Annual Review of Biophysics. PMID: 30857400
Crickard JB, Greene EC. Biochemical attributes of mitotic and meiotic presynaptic filaments. (2018) DNA Repair. PMID:30195641
Crickard JB, and Greene EC. The biochemistry of early meiotic recombination intermediates. (2018) Cell Cycle. PMID: 30482074