1: INDUSTRY OVERVIEW: DEPARTMENT STORES
Department stores are large retail outlets that contain numerous individual shops, providing a wide range of product lines. Department stores most oftentimes consist of the following product categories:
1) Food
2) Cosmetics
3) Shoes and Accessories
4) Clothing
5) Interior Décor
6) Restaurants
Depending on the type of department store, department stores can offer a much wider range of products, including furniture, toys, electronics, books, etc.
Department stores come in a wide range of qualities and prices. There are such things as “high-end department stores”, which would focus purely on offering high-profile brands and products, while there are more mass-market targeting department stores, which are more likely to include a wider range of products, including practical household products.
That said, department stores will oftentimes try to cater to specific types of market segments. Particularly in the case of department stores in large cities, each department store will try to position itself differently from its direct and nearby competitors: some will try to cater to younger generations, while some will try to cater to the older generations. Some will try to cater to those interested in mainstream brands, while others will focus more on boutique, independent brands.
In the US, the department store industry includes approximately 20 companies operating roughly 3,500 stores. Major department stores in the US include: Sears, JCPenney, Macy’s, and Dillard’s. The industry earns an annual revenue of around $60 billion USD, 95% of which is earned by the largest 8 companies in the industry.
Some links about the industry:
http://en.wikipedia.org/wiki/Department_store
http://vspages.com/mall-vs-department-store-5580/
http://en.wikipedia.org/wiki/Shopping_mall
http://www.hoovers.com/industry/department-stores/1529-1.html
SPACE
2a: Implicit or Explicit?
From the department store owner’s standpoint, I would say that space is often sold explicitly, as they would charge the tenants per the size of the lease space. On the other hand, for stalls or booths set up in more open areas of the department store, space may be considered more implicit, as these spaces may be sold with less correlation to the exact size of the space.
2b: Ways of Splitting Space
Department stores have different types of spaces within the building that cater to their customers. The most typical type is the space split by fixed walls into one unit, and can usually be shut off or closed by a door or a shutter. These spaces cannot easily be adjusted in terms of size and layout without investment of significant time and money. These fixed spaces are generally leased out to a specific brand or company, such as Zara, Coach, Burberry, etc.
Then there is the semi-fixed space, such as the department store areas dedicated to selling cosmetics or shoes. These are oftentimes open areas in which a specific brand or merchandising line take up certain spaces, but are not divided up by physical walls or entryways. These areas are much more flexible in terms of changing the products being handled, given that one area can easily be changed to carry one brand/line from another; however, certain fixtures used for the displays will be fixed, and hence less flexible to change from a layout perspective.
There is also open space, in which temporary booths or stalls are built to sell a smaller line of products or services.
Different from other uses of store space is the use of space to purely focus on selling experiential services. For department stores, the focus generally remains on selling physical products. However, there are rare instances when space is allocated to selling services—one case being when department stores are attached to movie theaters.
2c: Creating Additional Revenue
One of the most standard ways for department stores to create additional revenue is by holding major seasonal sales. Because the product life cycle of clothes tends to be fairly short, many stores have inventory left over by the time they have to replace old products with new products. Having a highly publicized sale allows for these leftover products to be sold, be it at a lower price than its retail value.
One key to making people spend more money is to convince people to stay out shopping longer. A way to
do this is to provide adequate opportunity for people to take a break from shopping and rest. Many department stores provide these venues by creating food courts—or in high-end places by providing patisseries or coffee shops at which people can recharge before going back to shop some more.
I also think one of the more creative ways in which department stores have used their space to create additional revenue is through creative use of its open space. Another approach department stores can use to bring people to their stores is to provide an additional incentive to go to that location. A common approach used to achieve this in the U.S. has been to create playgrounds in the open areas of the department stores. This service often incentivizes families to go to a department store, simply because it allows an opportunity for their children to play.
One more approach commonly used in Japanese department stores to bring more people to the site is to host certain “festivals” or special events in their open space. For example, department stores would often host weekly “mini fairs” on either the ground floor or the top floor, in which one area of the department store would be devoted to hosting jewelry/clothes/food from brands and shops that usually were not represented at the department store. The content would be changed frequently, and the department store would often be able to bring new people into the store by publicizing new, limited-time genres of offerings at their store.
2d: Potential New Ways of Splitting Space
There are several different directions department stores could potentially go in terms of splitting space differently. One direction would be to use space to create more personalized services to customers. Many of the spaces in department stores are “public”, but allocating a portion of space at high-end stores to allow for “private” space may allow for varying experiences for customers. Customers would be charged a premium for making use of these private spaces.
Another potential use may be to make the spaces more flexible. Instead of sticking with a model that leans heavily toward having “fixed” spaces, changing to a model in which it would be much simpler, cheaper, and quicker to change tenants may be an attractive approach for department stores that are pursuing a more trendy, up-to-date feel.
3: TIME
3a: Implicit or Explicit?
Department stores generally sell time implicitly: this is because the product being sold generally isn’t associated with a particular time limit. For example, it is not like a massage, where you are buying 60 minutes worth of service. The transaction is associated with a physical product unattached to time.
3c: Selling Time Explicitly
Time is currently being sold explicitly at certain department stores, although these cases are generally not a reflection of its overall business model. For example, some department stores may include shops that offer time-explicit services. Some department stores have massage shops, which are time-based service sales.
As another example, some department stores in Japan have small football fields on their rooftops, which people can rent out on an hourly basis.
(http://www.futaba-sp.com/omiya/2010/03/post-23.html)
Some department stores also include game centers for children—some of these entertainment options include machines that run for a set period of time per game.
Department stores will often have restaurants on one of their floors. These restaurants can often choose to set time limits to each group of customers (ex. 2hr limit) to be able to take in more customers during peak times.
(http://www.mitokeisei.co.jp/shop/10_skygarden/11keizan.html)
3d: Creative Things to do with Time
There are a couple things that could be done creatively with time—some of which may already be being done to varying lengths at department stores. One might be to offer some sort of benefit if a certain amount of time is spent within the department store. For example, if a customer was to receive certain benefits if they stayed for 5 hours at a department store on an off-peak day, this could incentivize customers to spend more money during their wait time, and this could also help to improve the image of the department store by maintaining more customers.
Another thing they might potentially consider doing is to include shops that provide rental services. Some shops may already do tuxedo/dress rentals, which would be time-based; they could potentially take this further by doing time-based rentals of other high-end luxury clothes and accessories.
4a/b: Physical and Non-Physical Rate Fences
Below are several examples of physical rate fences (owner-tenant relationships are more likely to be involved with physical rate fences than the tenant-customer relationships)
- (Owner-tenant POV) Depending on the size of the space being rented, owners can choose to increase or decrease the rates
- (Owner-tenant POV) Certain areas of a department store are likely to be more popular/convenient; hence an owner can charge more depending on the location of the space within the store (http://www.ehow.com/facts_6313023_average-retail-lease_.html)
- (Tenant-customer POV) For services such as restaurants within the department store, tenants can set rates by charging differently between open areas and private rooms
In terms of non-physical rate fences, I would say that there are many opportunities to create rate fences, depending on the type of service/product the store sells. There are also several opportunities within the owner-tenant relationship:
- (Owner-tenant POV) Depending on the lease period, the owner can set different rates to charge the tenant
- (Owner-tenant POV) Depending on the credibility/attractiveness of the tenant, the owner can set different rates
- (Tenant-customer POV) Depending on the quality of the product, functionality of the product, or time/length of the service, rates can be set differently. There is an enormously wide range of examples of this in department stores. A Gap outlet, for example, may sell a tank top for $10, while a Burberry outlet would sell a similar styled tank top for $150. Similarly, a cell phone with 3G functionality may sell at a cell phone provider outlet at a certain price, while a phone with 4G functionality would sell at a much higher price.
4c: Creative Ways to Set Rate Fences
Some ways I can think of setting rate fences creatively is to perhaps offer more intangible services—rather than just the physical products. For example, an I Love Bangkok t-shirt may only cost $5 at the actual retail shop, but if the customer already knows what he/she wants, but doesn’t want to make the trip up 7 floors and 5 minutes of walking to get there, the store could potentially charge an extra $1 to have the t-shirt brought down to the concierge desk of the department store for a quick pick-up.
AS101 order
Furthermore, an aptamer-based fluorescent biosensor for metronidazole was constructed based on AP32-4. With the help of exonuclease-assisted target-recycling amplification, the biosensor exhibits a linear detection range of 25-800 nM, and the detection limit of 10.50 nM. The biosensor was applied to detect metronidazole in honey samples. The results show that not only an efficient strategy for screening robust and practic
read more
The results suggest that the physical activity-based program has the potential to improve elementary school children´s health literacy, even though in a single group pilot study.This research was motivated by the nurses’ decision-making process in the current emergency department (ED) triage process in the United States. It explores how continuous vital signs monitoring can be integrated into t
OTX008 nmr
We conclude with a discussion of General Data Protection Regulation (GDPR) and the practical, philosophical, and policy challenges associated with communicating food safety and nutrition information digitally.Human phonemics responds to an urgent need in the medical research community; namely, reproducibility.
We sought to assess longitudinal electronic health records (EHRs) using machine learning (ML)
AdipoRon agonist
Finally, we propose an algorithm of increasing the number of clusters when the coefficient of variation of cluster sizes is known and unknown.Glutaredoxin (GRX) plays an essential role in the control of the cellular redox state and related pathways in many organisms. There is limited information on GRXs from the model nitrogen (N2)-fixing bacterium Azorhizobium caulinodans. In the present work, we identified and p
https://www.selleckchem.com/products/dotap-chloride.html
Furthermore, in vitro cytotoxicity test indicated no cytotoxicity for the improved formulation of niosome containing arbutin. The cell viability (HFF cell line) for niosomal formulation of arbutin was reported to be about 86 %. The formulations were examined in terms of skin irritation on Wistar rats, and non-irritancy of arbutin niosomal gels was indicated. The findin
this website
However, anodal iontophoresis resulted in significant amounts of co-encapsulated CDDP and DTX being deposited in the buccal mucosa; e.g., after current application for 10 min, the deposition of CDDP and DTX was 13.54 ± 1.78 and 10.75 ± 1.75 μg/cm2 cf. 0.20 ± 0.07 and 0.19 ± 0.09 μg/cm2 for the passive controls-i.e., 67.7- and 56.6-fold increases-without any noticeable increase in their transmucosal permeation. Con
A mesothelioma or asbestos Claim lawyer can assist victims and their families collect compensation from sources such as trust funds, VA
benefits and personal injury lawsuits.
learn more
Understanding the evolution of the structure and properties in metals from molecule-like to bulk-like has been a long sought fundamental question in science, since Faraday’s 1857 work. We report the discovery of a Janus nanomolecule, Au191(SPh-tBu)66 having both molecular and metallic characteristics, explored crystallographically and optically and modeled theoretically. Au191 has an anisotropic, singly twinned struct
GANT61
The global status of dioxin emissions across 150 countries/regions were compiled in this study. China, the major emitter of dioxin and the largest developing country, was chosen as an example to illustrate its emission reductions. The global dioxin emissions were about 97.0 kg TEQ/year, Asia and Africa emitted the most dioxins among the continents. Globally, open burning processes were the most important sources of dioxins. D
6-Thio-dG cell line
Smoking (OR 3.505; p = 0.028), non-steroidal anti-inflammatory drugs intake (OR 3.473; p = 0.021) and small intestine bacterial overgrowth (OR 3.172; p = 0.013) were independent risk factors for altered fecal calprotectin in the absence of endoscopic lesions. No association was found for any of the other variables. CONCLUSIONS smoking and the use of non-steroidal anti-inflammatory drugs are strongly associated
Resveratrol
re effective than single-dose MTZ for trichomoniasis, this advantage is not as obvious as previously proven. This small advantage may be lower if considering the compliance of multidose MTZ in the real world. Therefore, more high-quality studies are needed to confirm this before suggesting a multidose MTZ as the first line treatment for HIV-negative trichomoniasis.
The placental cord insertion (P
BV-6 nmr
Needlescopic TEP is a useful procedure that decreases operative duration with no significant differences in perioperative morbidity compared with conventional TEP.
Needlescopic TEP is a useful procedure that decreases operative duration with no significant differences in perioperative morbidity compared with conventional TEP.The utilization of endoscope-assisted surgery is becoming a more common modality fo
learn more
The capabilities of MPI opens the potential for several applications of MPI in neurocognitive disorders, including vascular imaging, detection of amyloid plaques and potentially other pathological hallmarks of Alzheimer’s disease and stem-cell tracking.
The capabilities of MPI opens the potential for several applications of MPI in neurocognitive disorders, including vascular imaging, detection of a
AR-42 chemical structure
The post is reinserted, excess resin cement is removed, and the cement is polymerized. This technique reduces the volume of resin cement required in each step and consequently the polymerization contraction stress. The 2-step technique is a simple method and a useful option for flared root canals.This study aimed to evaluate the fracture resistance of the bond between an artificial acrylic resin tooth
click here
strategies and healthcare systems.
Researchers have begun delivering mindfulness and aerobic exercise training concurrently on the premise that a combination intervention will yield salutary outcomes over and above each intervention alone. An estimate of the effect of combination training on chronic psychosocial stress in a nonclinical population has not been established. The objective of this stud
selleck chemical
Sensitive skin is characterized by uncomfortable sensations in response to a number of factors. We performed a large-scale study to investigate the prevalence of sensitive skin at all ages and the impacts of related factors across China.
A nationwide sampling of the Chinese population aged over 18 was conducted. Subjects were categorized into sensitive a
this website
Soybean isoflavone aglycones have been investigated as potential wound healing compounds for topical application. The aim of this study was to evaluate the wound healing properties of a soybean isoflavone aglycones-rich fraction (IAF) when incorporated into lipid nanoemulsions dispersed in acrylic-acid hydrogels. Formulations exhibited a mean droplet size in the sub 200 nm range, negative ζ-potential (-60 mV), and displa
Selpercatinib
In uniform temperature treatments, the distribution shifted toward high DO levels, especially in uniform high temperature, confirming that Tigriopus can sense environmental pO2. These results question the ecological relevance of OCLTT for Tigriopus and raise the possibility of microhabitat selection being used within splashpool environments to avoid physiologically stressful combinations of conditions.Mother-child in
Abemaciclib cell line
Mediation analysis showed that parental cognitive empathy had an indirect effect on children’s emotional/behavioral problems through children’s social competence.
Parental empathy may have a subtle influence on the social competence of school-aged children, which further affects the severity of children’s emotional/behavioral problems.
Parental emp
find more
CNN results were compared with three benchmark ML methods Support Vector Machine, Random Forest and regularized Linear Discriminant Analysis. Intra- and inter-subject methods of HP optimization were tested and the effects of HPs statistically analyzed. Accuracies obtained by the CNNs were significantly greater than the benchmark methods when trained on both datasets (words 24.97%, p less then 1 × 10-7, chance 16.67%; v
AS101
Quantitative Electroencephalogram-(QEEG-)informed neurofeedback is a method in which standard neurofeedback protocols are assigned, based on individual EEG characteristics in order to enhance effectiveness. Thus far clinical effectiveness data have only been published in a small sample of 21 ADHD patients. Therefore, this manuscript aims to replicate this effectiveness in a new sample of 114 patients treated with QEEG-informed
best bunk bed reviews
The Best Affordable Bunk Beds
Think about factors like the dimensions of your room as well as the height of your ceiling, and whether or not you’d like a guardrail or trundle. IKEA’s Mydal is a great choice. It’s durable simple, sleek, and priced less than other bunk beds.
Find a bun
Sivelestat
whelmingly high in the study area. The study findings suggest that because of the exceptionally high levels of malaria transmission in the study area, malaria elimination cannot be achieved solely by mass deployment of ITNs and additional control measures are needed.
The aim of this study was to gain consensus on an evidence informed physical activity policy template for early childhood educ
mTOR inhibitor
Fetal alcohol spectrum disorder (FASD) is characterized by developmental and behavioral deficits caused by maternal drinking during pregnancy. Children born with FASD often face additional stresses, including maternal separation, that add yet additional deficits. The mechanism associated with this interaction is not known. We have used a mouse model for prenatal ethanol exposure and maternal separation to demonstrate
selleck chemicals llc
Twenty yeast isolates identified as Aureobasidium pullulans, Cryptococcus magnus, Metschnikowia pulcherrima and Rhodotorula glutinis presented positive antagonistic activity against Penicillium expansum; they controlled the development of at least one of the fungi, significantly reducing the disease incidence. The results showed that three antagonistic yeasts (M. pulcherrima 22, 36 and 43) r
텐텐벳주소
우리카지노는 국내 최대 규모의 온라인카지노로서 2007년부터 정부의 표적이 되었으며 지속적인 정부 단속을 받고 있습니다. 따라서 우리는 사이트 이름을 Our Casino로 지정하고 Our Casino Affiliate라는 계열사 운영 회사를 설립했습니다.
매년 우리는 카지노 사업부의 이름을 바꾸고 원활하게 작동합니다.
Our Casino의 2021년 인수 계획에 따르면 Sans Casino, 007 Casino, Merit Casino, Coin Casino, First Casino 및 Duzon Casino의 6개 카지노 계열사가 제공됩니다.
우리 카지노는 Our Casino라는 큰 그
find more
Due to the diversity of sulfur valence in cobalt-based sulfides, it is difficult to control the crystal phase and composition of the products during synthesis. Herein, a one-pot hydrothermal method is reported to self-assemble the cobalt sulfides (CoS2, Co9S8and Co3S4) with hollow nanostructures. The whole preparation process is simple and mild, avoiding high temperature calcination. The performances of the three kinds of
find more
The aim of this study was to investigate the effect and risk management of early mobilization in the intensive care unit (ICU) with multidisciplinary collaboration and daily goal planning.
Rehabilitation of ICU patients in our hospital between April 1, 2019, and September 30, 2019, was investigated retrospectively. The following factors were evaluated age and sex of the
LY3473329
As a public health measure during the COVID-19 pandemic, governments around the world instituted a variety of interventions to ‘flatten the curve’. The government of Maryland instituted similar measures. We observed a striking decline in paediatric intensive care unit (PICU) admissions during that period, mostly due to a decease in respiratory infections. We believe this decline is multifactorial less person-to-person
OTX008 nmr
We conclude with a discussion of General Data Protection Regulation (GDPR) and the practical, philosophical, and policy challenges associated with communicating food safety and nutrition information digitally.Human phonemics responds to an urgent need in the medical research community; namely, reproducibility.
We sought to assess longitudinal electronic health records (EHRs) using machine learning (ML)
ADHD in adults symptoms uk
What Are ADHD Symptoms in Adults?
Adults who think they have ADHD should first seek a diagnostic evaluation by a health care provider or mental health professional. The evaluation should include an interview with the person and a review of symptoms.
A person must have a minimum
Kynurenic acid antagonist
0.23641/asha.11984364.We recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, we report that EBV and high-risk HPVs are co-present in colorectal cancers from Syria. We reveal that 17 (~17%) of 102 cancer samples are positive for both EBV
https://www.selleckchem.com/products/abbv-2222.html
Patients in the MI group showed a faster recovery of physical activity in the immediate postoperative period and superior HRQoL in the first 3 months (both p<0.001) versus the MS group. Differences between the MI and MS group were indistinguishable over a longer follow-up. A similar correlation was observed in the frailty subanalysis. Overall, the MS group had a higher cumula
4-Phenylbutyric acid
Conclusions Only the new Index26 performed at a level comparable to the very strongest established formulas. All other new formulas had lower performance than was claimed in the original publications, underscoring that independent verification of new formulas is indispensable.Infective endocarditis (IE) is defined as infection of the endocardial surface of the heart which may involve heart v
range style dual fuel cookers
Reconditioned Dual Fuel Range Cookers
A range cooker is a staple item in any kitchen but it doesn’t have to be expensive. Reconditioned dual-fuel range cookers offer the perfect opportunity to reduce costs while preserving the quality.
They combine the advantages of elec
see more
There are also fewer somatic memory genes such as FLRT2, ADAMTS1, and FOXR1, which are abnormally activated or suppressed in early-dividing cloned embryos. These results show that early-dividing SCNT embryos have different transcriptional profiles than late-dividing embryos. Early division of SCNT embryos may be associated with their better reprogramming capacity, and somatic memory genes may act as a reprogramming barrier i
https://99ok-bet-2.blogbright.net/99ok-trai-nghiem-dinh-cao-thang-lon-moi-ngay-1733995391
99ok là thiên đường giải trí trực tuyến hàng đầu, chiêu đãi bạn với kho game khổng lồ và đa dạng. Với chất lượng game đỉnh cao và tỷ lệ trả thưởng hấp dẫn, 99ok chắc chắn sẽ mang đến cho bạn những trải nghiệm khó quên.
THÔNG TIN
Địa chỉ: 10 P. Đào Tấn, Ngọc Khánh, Ba
symptoms of ADHD in adults female
ADHD Symptoms in Adults Quiz
Adults can use online ADHD tests and rating scales to determine if they are suffering from symptoms. These ratings can be helpful however, a physician must examine an adult to determine if they have an assessment of ADHD.
These tests will require you to rate how often you experience specific ADHD symptoms. They can help
https://taniarata.pl
Frank szwajcarski, jako stabilna waluta, miał być gwarancją niskich rat i przewidywalności spłaty. Wielu klientów, którzy zaciągnęli takie kredyty, znalazło się w trudnej sytuacji finansowej, z której nie było łatwego wyjścia.
Schemat działania kredytów frankowych
W momencie zaciągania kredytu kurs franka był niski, co sprawiało, że kredyt wydawał się korzystniejszy niż ten w złotów
read more
13/14 (93%) of RT-PCR-positive and none of the RT-PCR-negative HCWs had a positive humoral response Higher IgG indexes were observed in individuals over 50 years of age (14.5 ± 7.7 vs. 5.0 ± 4.4, p = 0.012). Of 617 rheumatic patients, 8 (1.3%) developed COVID-19 symptoms (1/8 hospitalization, 8/8 complete recovery), following a consultation/procedure with an asymptomatic (7/8) or mildly symptomatic (1/8) HC
read more
Moreover, an exploratory study showed that the rapid clearance of
Zr-C4 scFv enabled detection of endogenous PD-L1 on a genetically engineered and orthotopic model of hepatocellular carcinoma.
In summary, these data support the use of low molecular weight constructs for PD-L1 imaging, especially for tumor types that manifest in abdominal organs that are obstructe
compound library inhibitor
ted that Aβ not only accelerates tau aggregation/neuroinflammation but promotes its toxicity. Our findings showed the importance of understanding the role and therapeutic potential of the interaction between amyloid and tau aggregation/neuroinflammation in Alzheimer’s disease.It is a challenge to explore photocatalytic materials for sunlight-driven water splitting owing to the limited choice of a single s
buy MPP+ iodide
The last patient required prolonged hospitalization in the intensive care unit. Clinicians should be vigilant in monitoring these possible complications, as no standards of care exist for the initiation of enteral nutrition for this unique population.
To demonstrate an MRI pulse sequence-Sub-millisecond Periodic Event Encoded Dynamic Imaging with a reduced field of view (or rFOV-SPEEDI)-for de
read more
A 41-year-old female captive gorilla with progressive weight loss and hydrothorax of unknown origin was euthanized and submitted for necropsy. The ascending aorta showed intimal aortic thickenings, consistent with so called ‘tree bark’ changes. Microscopic examination revealed a non-infectious, necrotizing and granulomatous aortitis with no evidence of systemic vasculitis or infectious disease elsewhere in the body
click here
ack African and Caribbean people and that the context of therapy (inpatient vs community settings) has a relationship with disparity in access to treatment.Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, the effectiveness of different NPIs at reducing transmission is poorly understood. We gathered chronological data on the implementation of NPIs for several
https://anotepad.com/notes/px48hya8
Trong thế giới của ngành giải trí trực tuyến, nhà cái Goal123 đã nhanh chóng nổi lên như một trong những cái tên đáng chú ý dành cho những người yêu thích cá cược thể thao và các trò chơi trực tuyến. Với một nền tảng hiện đại và giao diện thân thiện, Goal123 không chỉ mang đến cho người chơi trải nghiệm mượt mà mà còn mở ra nhiều cơ hội thắng lớn cùng những tính năng hấp dẫn. Tuy nhiên, bên cạnh những tiềm
best fridge brands uk
Best Refrigerators Brands
Whether you’re changing an old fridge, purchasing a second fridge for the garage or getting a small refrigerator for the office, picking the best brand name is very important. Search for brand names with resilient fridges, that are easy to clean and that offer the features you need.
Samsung stands out at household
WAY-316606 molecular weight
pnea assessment, ascertainment and management of potentially reversible causes, and referral to an interdisciplinary palliative care team. Nonpharmacologic interventions that may be offered to relieve dyspnea include airflow interventions (eg, a fan directed at the cheek), standard supplemental oxygen for patients with hypoxemia, and other psychoeducational, self-management, or complementary approache
find more
A dual electronic basis set approach is introduced for more efficient but accurate calculations of the anharmonic vibrational spectra in the framework of the vibrational self-consistent field (VSCF) theory. In this approach, an accurate basis set is used to compute the vibrational spectra at the harmonic level. The results are used to scale the potential surface from a more modest but much more efficient basis set. The scaling is such that at
see more
Furthermore, prophylactic and therapeutic injection of HS1 mAb into C57BL/6 mice significantly improved the survival rate following lethal infection with an STSS clinical isolate. These results highlight the therapeutic potential of HS1 mAb for STSS treatment.
We focused on mAbs that had originally been established as neutralizing reagents to perfringolysin O (PFO), another memb