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Our research aims to elucidate the molecular basis of aging and age-dependent pathologies.

We use the powerful genetic model Caenorhabditis elegans to identify and functionally characterize the  conserved molecular pathways important for longevity.  We then test whether our findings in C. elegans also hold true in mammalian cells. 

A better understanding of the basic biology of aging will have important implications for the prevention and treatment of many crippling age-dependent diseases, such as cancer, late onset diabetes, and neurodegeneration.