$2.5M grant funds research on tuberculosis treatment

Kaley M. Wilburn/Provided M. tuberculosis within macrophages were engineered to turn yellow-green when they eat cholesterol, left, and remain red when infected cells are treated with a compound that blocks bacterial cholesterol metabolism, thereby starving the pathogen, right. Cornell researchers are investigating compounds they identified that offer hope for effective…

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Researchers identify immune cells that keep gut fungi under control

Dr. Iliyan Iliev and Dr. Irina Leonardi/Weill Cornell Medicine.Opportunistic fungus called candida albicans (red) engulfed by CX3CR1+ phagocytes (green) in the gut villi (blue). Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine…

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New host-microbe institute connects campus researchers

New host-microbe institute connects campus researchers

Esther Angert/Cornell Microbiology, CALS
Epulopiscium sp., the large cigar-shaped cells seen here, are giant bacterial symbionts of the tropical marine surgeonfish Naso tonganus.

The university has launched the Cornell Institute of Host-Microbe Interactions and Disease(CIHMID), an umbrella organization that brings together the wide-ranging community of Cornell researchers studying host-microbe biology and disease.

“The scope of the institute is host-microbe interactions ranging from beneficial to pathogenic in plant and animal hosts,” said Brian Lazzaro, the institute’s director and professor of entomology and of ecology and evolutionary biology.

The institute will provide a hub for researchers distributed across campus, and will initially include faculty from the Colleges of Agriculture and Life Sciences (CALS), Arts and Sciences, Veterinary Medicine, Engineering and Human Ecology. It will likely expand to Weill Cornell Medicine in New York in the future.

Research areas cover beneficial and pathogenic interactions between hosts (plants and animals) and microbes (bacteria, viruses and fungi), including veterinary immunology, clinical research, agriculture, natural systems and basic research.

“We have a lot of people doing this kind of work at Cornell,” Lazzaro said. “By nature of the distribution [of researchers across campus] it means we can have more people working in these different areas without overloading a particular unit. But it also means people can be dispersed, and that’s not always optimal for interdisciplinary collaboration and communication.”

To start, the institute will offer:

  • a postdoctoral fellows program with two-year appointments, where postdoc researchers will be encouraged to bridge disciplines and groups;
  • a seminar series that will fund and invite high-profile speakers to campus;
  • undergraduate research internships;
  • facilitation and support for applying for large center grants, training grants and multiple-principal investigator grants among CIHMID faculty;
  • an annual research symposium; and

The institute will take advantage of existing graduate curricula, and will be affiliated with the College of Veterinary Medicine’s Master of Public Health program and the new Cornell-led Northeast Regional Center for Excellence in Vector Borne Diseases in the Department of Entomology.

The CIHMID is funded by CALS, the Office of the Provost, and the New York State Agricultural Experiment Station.

This article is written by Krishna Ramanujan and was published in the Cornell Chronicle on January 19, 2017.

$10M CDC grant funds center to fight vector borne diseases

Managing mosquito-borne viruses, such as West Nile, Dengue, Zika and tick-borne Lyme disease have been a challenge due to lack of resources, knowledge and trained expertise. To better understand, prevent and treat diseases passed from insects to people, the Cornell-led Northeast Regional Center for Excellence in Vector Borne Diseases will launch later…

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Haiti, Hurricanes and Cholera: a One Health Approach

Hurricane Matthew struck Haiti on October 4, 2016 and has acted as a deadly catalyst upon the country’s worsening cholera epidemic. The outbreak began in 2010 after the catastrophic earthquake, when contaminated waste from a United Nations peacekeeping base entered a nearby river.  In order to understand this epidemic from…

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Symposium looks at veterinary medicine in public health

The Cornell College of Veterinary Medicine (CVM) hosted the seventh annual Veterinary Public Health Symposium Sept. 9-11. Organized by student members of the Cornell Veterinary Public Health Association, the symposium featured talks by a broad range of veterinarians, epidemiologists and public health officials. The symposium commenced with the annual Poppensiek Lecture,…

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