Dando Lab recent article highlights effects of obesity on taste buds

A recently published PLOS Biology article Inflammation arising from obesity reduces taste bud abundance and inhibits renewal” by Andrew Kaufman, Ezen Choo, Anna Koh, and Robin Dando discussed the effects of obesity on taste buds in mice.

Researchers showed that regular mice, that were fed high-fat diet, predictably became obese.  They also started losing their taste buds, when compared to their littermates who were not obese.  However, obesity-resistant mice, that were also fed high-fat diet , did not become obese and did not experience changes in the number of  taste buds.

Researchers concluded that “taste loss is a metabolic consequence of the obese state rather than a response to oral exposure to fat.”

To read a full article, please go to…

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001959#sec007

https://doi.org/10.1371/journal.pbio.2001959

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