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Selvaraj Laboratory

of Integrative Physiology (SLIP)

Press release: Metabolic switch for storing chicken sperm

See new results from our collaborator on a technology for long-term liquid storage of chicken semen by arresting energy metabolism. Read the full press release at: https://phys.org/news/2023-12-technology-long-term-liquid-storage-chicken.html

The first metabolic framework for steroid biosynthetic regulation

Leydig cells are known for their tremendous demand for cholesterol during acute de novo biosynthesis of the male hormone. Looking beyond the essential cholesterol storage and mobilization, we uncover the molecular composition of MA-10 Leydig cells and describe different metabolic systems that support steroidogenic function. Functional testing via limiting use of specific metabolite stockpiles identified crucial components and novel paths to support steroid biosynthesis. Our findings build a metabolomic framework for steroidogenesis and provide new fundamental insights into its biosynthetic regulation.

Read the full paper: https://academic.oup.com/pnasnexus/article/1/4/pgac215/6724258

Kasey Schalich in colostrum feeding of calves

Kasey Schalich awarded NE-SARE grant

Kasey was awarded a competitive Northeast Sustainable Agriculture Research and Education (SARE) graduate student grant.

This project is to study transfer of passive immunity in neonatal calves. Absorption of colostrum IgG is critical for neonatal health. From the management point of view, efficient transfer of passive immunity prevents morbidity reducing antibiotic use in farms. As a result, it provides an economic advantage for dairy farms. From this study, we hope to provide a physiology-based recommendation for optimal colostrum management that would be beneficial for dairy farms.

[Click here for project information and updates]

Prasanthi, Tiffany and Michael Present at ASCB 2018

Tiffany Kei, Prasanthi Koganti and Michael Kern presented their research abstracts at American Society for Cell Biology annual meeting 2018. Tiffany presented her Honors research on bovine pluripotency, Prasanthi and Michael presented on cholesterol transport and metabolism during steroidogenesis.

Shannon-Samantha-Josh: Undergraduates awarded research support


From left:

Shannon Reddy was awarded the USDA supplement. Samantha Maloy was awarded the CALS Charitable Trust award. Joshua Goddard was awarded the Jane E Brody Undergraduate Research fund.

Kanako’s paper selected as “Best of Basic Research” by the Endocrine Society

Best of Basic

Lan Tu selected as Cornell Vertebrate Genomics Scholar

Lan Tu was selected as the 2014 Vertebrate Genomics Scholar by the Center for Vertebrate Genomics (VERGE) at Cornell.

Isabel wins best poster award at the ABRCMS

Isabel Jimenez, Undergraduate Scholar in the lab presented her research at the Annual Biomedical Research Conference for Minority Students in San Antonio, TX, Nov 12-15, 2014 (http://www.abrcms.org/). Her poster was selected for the Best Poster Award at this meeting. Isabel is in the front row 5th from the left.

Lan’s paper featured on JBC Cover

Selvaraj_JBC_October3_cover

Lan’s paper entitled: “Peripheral benzodiazepine receptor/translocator protein global knockout mice are viable with no effects on steroid hormone biosynthesis”. This manuscript was also selected as “Paper of the Week”

Lan is also featured in this issue as a young scientist: http://www.jbc.org/content/289/40/27444/suppl/DCAuthor_profile

Please read press release by the American Society of Biochemistry and Molecular Biology: http://www.jbc.org/content/289/40/27455

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