New publication: Dielectrophoresis for cell and particle manipulations
Dielectrophoresis for cell and particle manipulations
Hawkins BG, Gleghorn JP, Kirby BJ
in Methods in Bioengineering: Biomicrofabrication and Biomicrofluidics, Ed. J.D. Zahn, Artech Press, 2009.
Abstract
In this chapter, we will explore the use of dielectrophoresis (DEP) for particle and cell manipulation. This is a broad field, and so our aim will be to present the theory behind several dielectrophoresis techniques, as well as specific experimental recipes. Initially, we will present the concept and theoretical underpinnings of DEP and build a framework of approximations that connect our theoretical development to engineering design and experimental implementation. First, from a theoretical perspective, we will approach DEP techniques based on the properties of the driving electric field and introduce experimental techniques for manipulating these field properties. Next, from an experimental perspective, we will approach DEP techniques based on device geometries used to generate electric field non-uniformities and report specific methodologies for reproducing experimental results. Finally, from a design perspective, we will present DEP techniques based on the resulting motion of particles in the system and examine a variety of demonstrated applications.